Heavy Weight Time Scale

1 day

1 month +1,5 log

1 year + 1,1 log

non reciprocity Schartzshields

what to erase?

daily activities

traces of daily activities

Limited means, Unlimited minds

On the 2004 Nobel Prize.

Hershko, Rose and Ciechanover, in their respective Nobel Lectures, reminisce on how the concept arose, how difficulties and misconceptions were overcome, how an experimental model was identified, how technologies slowly improved, how experimental evidence gradually built a novel molecular mechanism, how pharmacological modulators were identified, and how these progressed from the lab to the clinic. The concept was unprecedented: a 2.5 million Dalton protease, three tagging enzymes and a large protein tag. However, the most interesting, and unusual aspect of these lectures is the opportunity to see the individual personalities of these investigators. The three interviews bring to the attention of our reader, and to young scientists in general, the determination, perseverance, logic and experimental stringency of young scientists with limited means and unlimited minds. 

G Melino on behalf of The Editors Cell Death & Differentiation volume 12, pages1155–1157 (2005)Cite this article

Actinographics

This project is an apology of fluidity and a re•presentation of chaos

Fluidity is the condition of movement and the essence of time • My sensitive canvas is stretched over water • I pay homage to this liquid state, so rare in the Universe, which contains practically only gases and rocks • The liquid state is a condensed state, heavy like a solid, but fluid like a gas, and like ink or paint •On Earth, water forms this liquid state. It is essential to life, and only in liquid form • Only in this state is it possible for molecules in solution to move, hybridize and separate • It dissolves pigments, enabling them to form all colors • Its fluidity does not diminish its strength • It also drags away the densest solids, transforming rocks into sand • It is the only liquid in the Earth's atmosphere. Living beings have also created other liquids : oils, which form the fluid boundaries of our cells • making them mobile and flexible • Fluidity is also the necessary essence of time • Photography, which requires a perfect command of shutter time, is ultimately a way of manifesting the existence of time. In painting, the liquid state is as essential as in life. This state is provided by water, the cosmic mineral that enables life, or by oil, the organic product of life. The fluidity of paint is essential • It enables the blending of colors and the creation of shapes. My paintbrush is the ray that comes directly to me from the midday sun at its zenith in a perfect straight line • Less than ten minutes after being born into the sun, it is reflected by the surface of the water that I contemplate without controlling it • And it becomes my paintbrush, made mobile and flexible by the untameble undulations of the water's surface • (figure 1)

Figure 1 | diagram of actinographic photography

On my photosensitive canvas, he produces traces that are slow or fast, open or closed, simple or complex • As Martha Holmes shows us in her photos, Pollock is on his knees on his canvases, and the liquid color flows directly onto the canvas, it is the combined actions of the weight of the liquid, its viscosity and the movement of the hand that create the traces.I capture the trace I want by opening the shutter for a period of time adapted to the ripples of the water • In the form provided by the liquid state in motion, I put the colors I also draw from nature • In each trace of the white color of the sun, which contains all colors, I choose one color, extracted from a real landscape • And with the help of colored traces, I make visible my landscape, my sky, my earth, my rivers and seas dissolved in the cosmic chaos that generated them •.Art doesn't reproduce the visible, it makes visible what you, the observer, think • The random variable of water is the key to my communion with you, whose imagination will recreate me •

---